Diego Jota, Wataru Endo, Darwin Nunez, Ryan Gravenberch, and Salah scored to beat Toulouse 5-1 at Anfield on Thursday.
After coming on with 20 minutes left, the Egyptian winger scored a stunning goal in the 93rd minute.
It was his 43rd goal in major European tournaments for Liverpool, the most by an English player.
41 were Champions League goals, while two were Europa League goals this season.
It beats Henry’s 42 at Arsenal—35 in the Champions League and seven in the UEFA Cup.
Salah already holds the record for most Champions League goals for an English team, most UEFA club competition goals by an African player, and Liverpool’s all-time top Premier League and European striker.
“It’s really easy to fall in love with this team because there is a lot of excitement there,” Jurgen Klopp remarked after the Toulouse win.
You saw the hard times. Most of the time, we ruled.
We scored well, nobody was hurt—perfect night. We could invite the kids.
Liverpool leads Group E by five points over Union Saint-Gilloise, Toulouse, and LASK after winning all three Europa League games this season.
Salah will have his first chance to improve his record on November 9 when they visit France.
Before then, he’ll try to maintain Liverpool’s strong start to the Premier League against Nottingham Forest on Sunday.